Immunogenicity of Salmonella typhi Ty21a vaccine for young children.
نویسندگان
چکیده
An attenuated Salmonella typhi Ty21a vaccine was administered to 18 infants and toddlers (less than or equal to 24 months old) to determine its safety and immunogenicity. The vaccination (10(9) CFU per dose, three doses) was well tolerated. However, after the vaccination there was no evidence of a humoral or cellular immune response to S. typhi. The vaccine used was known to be immunogenic for older children and adults. The results support the view that the immunogenicity of Ty21a is age dependent.
منابع مشابه
Safety and immunogenicity of Salmonella typhi Ty21a vaccine in young Thai children.
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عنوان ژورنال:
- Infection and immunity
دوره 59 11 شماره
صفحات -
تاریخ انتشار 1991